Xəbərlər AMEA Biologiya və tibb elmləri bölməsinin rəsmi jurnalı
Study Of The Azerbaijan Population By The STR Markers: I. Definition of Basic Population-Genetic Parameters Of The STR Markers
N.Sh. Mustafayev, A.Ch. Mammadov, E.R. Mammadov, A.B. Hasanov, I.M. Huseynova

Institute of Molecular Biology & Biotechnology, Azerbaijan NAS,

Scientific-Practical Unit of Anatomical Pathology and Forensic Medical Examination, 

Ministry of Health of the Republic of Azerbaijan


   Azerbaijan population has been investigated using 15 STR markers that constitute the basic set of human identification. In this study the chromosomal DNA isolated from 205 unrelated individuals has been used, and an allelic composition has been established for each STR marker. For each STR loci:  allele types (homo- and heterozygous), their actual (observed, Hobs) and expected (Hexp) frequencies, genetic diversity index (GD), power of exclusion (PE), power of discrimination (PD), polymorphic information content (PIC) have been calculated. Studies have shown that the number of identified homozygous alleles varies between 44-138, heterozygous alleles 272-366, the frequency of separate alleles between 0.0024-0.4951, the total frequencies of actually observed heterozygous alleles at loci 0.7171-0.8927, their expected frequencies whole locus (the degree of heterozygosity) 0.8184-0.9073, index of loci genetic diversity 0.6628-0.8748, loci exclusion ability (power) 0.3739-0.7805, discrimination power (probability) 0.8204-0.9095, and the poly­morphic information content 0.7946-0.8999. These parameters are quite high levels and the revealed frequencies of STR loci alleles can be recommended as reference frequencies in solving the various prob­lems of identification, including the forensic-medical examination practice.